Single-cell imaging of inflammatory caspase dimerization reveals differential recruitment to inflammasomes

The human inflammatory caspases, including caspase-1, -4, -5 and -12, are considered as key regulators of innate immunity protecting from sepsis and numerous inflammatory diseases. Caspase-1 is activated by proximity-induced dimerization following recruitment to inflammasomes but the roles of the re...

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Detalles Bibliográficos
Autores principales: Sanders, M G, Parsons, M J, Howard, A G A, Liu, J, Fassio, S R, Martinez, J A, Bouchier-Hayes, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650733/
https://www.ncbi.nlm.nih.gov/pubmed/26158519
http://dx.doi.org/10.1038/cddis.2015.186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650733/
https://www.ncbi.nlm.nih.gov/pubmed/26158519
http://dx.doi.org/10.1038/cddis.2015.186

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