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miR-205-5p-mediated downregulation of ErbB/HER receptors in breast cancer stem cells results in targeted therapy resistance

The ErbB tyrosine kinase receptor family has been shown to have an important role in tumorigenesis, and the expression of its receptor members is frequently deregulated in many types of solid tumors. Various drugs targeting these receptors have been approved for cancer treatment. Particularly, in br...

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Detalles Bibliográficos
Autores principales: De Cola, A, Volpe, S, Budani, M C, Ferracin, M, Lattanzio, R, Turdo, A, D'Agostino, D, Capone, E, Stassi, G, Todaro, M, Di Ilio, C, Sala, G, Piantelli, M, Negrini, M, Veronese, A, De Laurenzi, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650737/
https://www.ncbi.nlm.nih.gov/pubmed/26181203
http://dx.doi.org/10.1038/cddis.2015.192