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Blocking the epithelial-to-mesenchymal transition pathway abrogates resistance to anti-folate chemotherapy in lung cancer

Anticancer therapies currently used in the clinic often can neither eradicate the tumor nor prevent disease recurrence due to tumor resistance. In this study, we showed that chemoresistance to pemetrexed, a multi-target anti-folate (MTA) chemotherapeutic agent for non-small cell lung cancer (NSCLC),...

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Detalles Bibliográficos
Autores principales: Liang, S-Q, Marti, T M, Dorn, P, Froment, L, Hall, S R R, Berezowska, S, Kocher, G, Schmid, R A, Peng, R-W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650740/
https://www.ncbi.nlm.nih.gov/pubmed/26181204
http://dx.doi.org/10.1038/cddis.2015.195