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Evaluation and integration of cancer gene classifiers: identification and ranking of plausible drivers

The number of mutated genes in cancer cells is far larger than the number of mutations that drive cancer. The difficulty this creates for identifying relevant alterations has stimulated the development of various computational approaches to distinguishing drivers from bystanders. We develop and appl...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Tian, Feng, Hu, Zhenjun, DeLisi, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650817/
https://www.ncbi.nlm.nih.gov/pubmed/25961669
http://dx.doi.org/10.1038/srep10204