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In silico evaluation and exploration of antibiotic tuberculosis treatment regimens
BACKGROUND: Improvement in tuberculosis treatment regimens requires selection of antibiotics and dosing schedules from a large design space of possibilities. Incomplete knowledge of antibiotic and host immune dynamics in tuberculosis granulomas impacts clinical trial design and success, and variatio...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650854/ https://www.ncbi.nlm.nih.gov/pubmed/26578235 http://dx.doi.org/10.1186/s12918-015-0221-8 |