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In silico evaluation and exploration of antibiotic tuberculosis treatment regimens

BACKGROUND: Improvement in tuberculosis treatment regimens requires selection of antibiotics and dosing schedules from a large design space of possibilities. Incomplete knowledge of antibiotic and host immune dynamics in tuberculosis granulomas impacts clinical trial design and success, and variatio...

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Detalles Bibliográficos
Autores principales:	Pienaar, Elsje, Dartois, Véronique, Linderman, Jennifer J., Kirschner, Denise E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650854/ https://www.ncbi.nlm.nih.gov/pubmed/26578235 http://dx.doi.org/10.1186/s12918-015-0221-8

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