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MiR-21 is required for efficient kidney regeneration in fish

BACKGROUND: Acute kidney injury in mammals, which is caused by cardiovascular diseases or the administration of antibiotics with nephrotoxic side-effects is a life-threatening disease, since loss of nephrons is irreversible in mammals. In contrast, fish are able to generate new nephrons even in adul...

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Detalles Bibliográficos
Autores principales: Hoppe, Beate, Pietsch, Stefan, Franke, Martin, Engel, Sven, Groth, Marco, Platzer, Matthias, Englert, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650918/
https://www.ncbi.nlm.nih.gov/pubmed/26577279
http://dx.doi.org/10.1186/s12861-015-0089-2