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Hepatitis C virus core protein modulates pRb2/p130 expression in human hepatocellular carcinoma cell lines through promoter methylation
BACKGROUND: Hepatitis C Virus (HCV) infection is associated with chronically evolving disease and development of hepatocellular carcinoma (HCC), albeit the mechanism of HCC induction by HCV is still controversial. The nucleocapsid (core) protein of HCV has been shown to be directly implicated in cel...
Autores principales: | Mileo, Anna Maria, Mattarocci, Stefano, Matarrese, Paola, Anticoli, Simona, Abbruzzese, Claudia, Catone, Stefania, Sacco, Rodolfo, Paggi, Marco G., Ruggieri, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650920/ https://www.ncbi.nlm.nih.gov/pubmed/26576645 http://dx.doi.org/10.1186/s13046-015-0255-1 |
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