DNMT1 mediates chemosensitivity by reducing methylation of miRNA-20a promoter in glioma cells

Although methyltransferase has been recognized as a major element that governs the epigenetic regulation of the genome during temozolomide (TMZ) chemotherapy in glioblastoma multiforme (GBM) patients, its regulatory effect on glioblastoma chemoresistance has not been well defined. This study investi...

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Detalles Bibliográficos
Autores principales: Zhou, Daoyang, Wan, Yingfeng, Xie, Dajiang, Wang, Yirong, Wei, Junhua, Yan, Qingfeng, Lu, Peng, Mo, Lianjie, Xie, Jixi, Yang, Shuxu, Qi, Xuchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650929/
https://www.ncbi.nlm.nih.gov/pubmed/26337869
http://dx.doi.org/10.1038/emm.2015.57

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650929/
https://www.ncbi.nlm.nih.gov/pubmed/26337869
http://dx.doi.org/10.1038/emm.2015.57

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