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Vaccination with Klebsiella pneumoniae-derived extracellular vesicles protects against bacteria-induced lethality via both humoral and cellular immunity

The emergence of multidrug-resistant Klebsiella pneumoniae highlights the need to develop preventive measures to ameliorate Klebsiella infections. Bacteria-derived extracellular vesicles (EVs) are spherical nanometer-sized proteolipids enriched with outer membrane proteins. Gram-negative bacteria-de...

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Detalles Bibliográficos
Autores principales: Lee, Won-Hee, Choi, Hyun-Il, Hong, Sung-Wook, Kim, Kwang-sun, Gho, Yong Song, Jeon, Seong Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650931/
https://www.ncbi.nlm.nih.gov/pubmed/26358222
http://dx.doi.org/10.1038/emm.2015.59