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FXR expression is associated with dysregulated glucose and lipid levels in the offspring kidney induced by maternal obesity

BACKGROUND: Maternal obesity is associated with dysregulation of glucose and lipid metabolism with consequent exposure of the fetus to an abnormal metabolic milieu. It is recognized that maternal obesity predisposes offspring to chronic kidney disease (CKD). We aimed to determine whether the nuclear...

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Detalles Bibliográficos
Autores principales: Glastras, Sarah J., Wong, Muh Geot, Chen, Hui, Zhang, Jie, Zaky, Amgad, Pollock, Carol A., Saad, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650952/
https://www.ncbi.nlm.nih.gov/pubmed/26583035
http://dx.doi.org/10.1186/s12986-015-0032-3