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Overexpression of p53 predicts colorectal neoplasia risk in patients with inflammatory bowel disease and mucosa changes indefinite for dysplasia

Background and aims: We previously demonstrated a significant colorectal neoplasia risk in inflammatory bowel disease (IBD) patients with mucosal changes indefinite for dysplasia (IND) and the potential diagnostic utility of p53 and cytokeratin 7 immunohistochemistry in IBD-associated neoplasia. The...

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Detalles Bibliográficos
Autores principales: Horvath, Bela, Liu, Ganglei, Wu, Xianrui, Lai, Keith K, Shen, Bo, Liu, Xiuli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650973/
https://www.ncbi.nlm.nih.gov/pubmed/26063242
http://dx.doi.org/10.1093/gastro/gov022