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MicroRNA expression signature of castration-resistant prostate cancer: the microRNA-221/222 cluster functions as a tumour suppressor and disease progression marker

BACKGROUND: Our present study of the microRNA (miRNA) expression signature in castration-resistant prostate cancer (CRPC) revealed that the clustered miRNAs microRNA-221 (miR-221) and microRNA-222 (miR-222) are significantly downregulated in cancer tissues. The aim of this study was to investigate t...

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Detalles Bibliográficos
Autores principales: Goto, Yusuke, Kojima, Satoko, Nishikawa, Rika, Kurozumi, Akira, Kato, Mayuko, Enokida, Hideki, Matsushita, Ryosuke, Yamazaki, Kazuto, Ishida, Yasuo, Nakagawa, Masayuki, Naya, Yukio, Ichikawa, Tomohiko, Seki, Naohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651127/
https://www.ncbi.nlm.nih.gov/pubmed/26325107
http://dx.doi.org/10.1038/bjc.2015.300