Fitness Inference from Short-Read Data: Within-Host Evolution of a Reassortant H5N1 Influenza Virus

We present a method to infer the role of selection acting during the within-host evolution of the influenza virus from short-read genome sequence data. Linkage disequilibrium between loci is accounted for by treating short-read sequences as noisy multilocus emissions from an underlying model of hapl...

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Detalles Bibliográficos
Autor principal: Illingworth, Christopher J.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651230/
https://www.ncbi.nlm.nih.gov/pubmed/26243288
http://dx.doi.org/10.1093/molbev/msv171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651230/
https://www.ncbi.nlm.nih.gov/pubmed/26243288
http://dx.doi.org/10.1093/molbev/msv171

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