Synonymous Genetic Variation in Natural Isolates of Escherichia coli Does Not Predict Where Synonymous Substitutions Occur in a Long-Term Experiment

Synonymous genetic differences vary by more than 20-fold among genes in natural isolates of Escherichia coli. One hypothesis to explain this heterogeneity is that genes with high levels of synonymous variation mutate at higher rates than genes with low synonymous variation. If so, then one would exp...

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Detalles Bibliográficos
Autores principales: Maddamsetti, Rohan, Hatcher, Philip J., Cruveiller, Stéphane, Médigue, Claudine, Barrick, Jeffrey E., Lenski, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651231/
https://www.ncbi.nlm.nih.gov/pubmed/26199375
http://dx.doi.org/10.1093/molbev/msv161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651231/
https://www.ncbi.nlm.nih.gov/pubmed/26199375
http://dx.doi.org/10.1093/molbev/msv161

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