Evolutionary Transition from Pathogenicity to Commensalism: Global Regulator Mutations Mediate Fitness Gains through Virulence Attenuation

Symbiotic interactions are indispensable for metazoan function, but their origin and evolution remain elusive. We use a controlled evolution experiment to demonstrate the emergence of novel commensal interactions between Pseudomonas aeruginosa, an initially pathogenic bacterium, and a metazoan host,...

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Detalles Bibliográficos
Autores principales: Jansen, Gunther, Crummenerl, Lena L., Gilbert, Felix, Mohr, Timm, Pfefferkorn, Roxana, Thänert, Robert, Rosenstiel, Philip, Schulenburg, Hinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651237/
https://www.ncbi.nlm.nih.gov/pubmed/26199376
http://dx.doi.org/10.1093/molbev/msv160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651237/
https://www.ncbi.nlm.nih.gov/pubmed/26199376
http://dx.doi.org/10.1093/molbev/msv160

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