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FGF8 is Essential for Functionality of Induced Neural Precursor Cell-derived Dopaminergic Neurons

Induced neural precursor cells (iNPCs) are one source of transplantable dopaminergic neurons used in cell therapy for Parkinson’s disease. In the present study, we demonstrate that iNPCs can be generated by transducing Brn2, Ascl1, Myt1L and Bcl-xL in a culture supplemented with several mitogens and...

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Detalles Bibliográficos
Autores principales: Lim, Mi-Sun, Lee, Soo Young, Park, Chang-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Stem Cell Research 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651287/
https://www.ncbi.nlm.nih.gov/pubmed/26634071
http://dx.doi.org/10.15283/ijsc.2015.8.2.228