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The Expression of the Ubiquitin Ligase SIAH2 (Seven In Absentia Homolog 2) Is Increased in Human Lung Cancer

OBJECTIVES: Lung cancer is the leading cause of cancer-related deaths worldwide. Overall 5-year survival has shown little improvement over the last decades. Seven in absentia homolog (SIAH) proteins are E3 ubiquitin ligases that mediate proteasomal protein degradation by poly-ubiquitination. Even th...

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Detalles Bibliográficos
Autores principales: Moreno, Paula, Lara-Chica, Maribel, Soler-Torronteras, Rafael, Caro, Teresa, Medina, Manuel, Álvarez, Antonio, Salvatierra, Ángel, Muñoz, Eduardo, Calzado, Marco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651316/
https://www.ncbi.nlm.nih.gov/pubmed/26580787
http://dx.doi.org/10.1371/journal.pone.0143376