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The Expression of the Ubiquitin Ligase SIAH2 (Seven In Absentia Homolog 2) Is Increased in Human Lung Cancer

OBJECTIVES: Lung cancer is the leading cause of cancer-related deaths worldwide. Overall 5-year survival has shown little improvement over the last decades. Seven in absentia homolog (SIAH) proteins are E3 ubiquitin ligases that mediate proteasomal protein degradation by poly-ubiquitination. Even th...

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Detalles Bibliográficos
Autores principales:	Moreno, Paula, Lara-Chica, Maribel, Soler-Torronteras, Rafael, Caro, Teresa, Medina, Manuel, Álvarez, Antonio, Salvatierra, Ángel, Muñoz, Eduardo, Calzado, Marco A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651316/ https://www.ncbi.nlm.nih.gov/pubmed/26580787 http://dx.doi.org/10.1371/journal.pone.0143376

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