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Assessment of Interactions between Cisplatin and Two Histone Deacetylase Inhibitors in MCF7, T47D and MDA-MB-231 Human Breast Cancer Cell Lines – An Isobolographic Analysis

Histone deacetylase inhibitors (HDIs) are promising anticancer drugs, which inhibit proliferation of a wide variety of cancer cells including breast carcinoma cells. In the present study, we investigated the influence of valproic acid (VPA) and suberoylanilide hydroxamic acid (SAHA, vorinostat), alo...

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Detalles Bibliográficos
Autores principales: Wawruszak, Anna, Luszczki, Jarogniew J., Grabarska, Aneta, Gumbarewicz, Ewelina, Dmoszynska-Graniczka, Magdalena, Polberg, Krzysztof, Stepulak, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651465/
https://www.ncbi.nlm.nih.gov/pubmed/26580554
http://dx.doi.org/10.1371/journal.pone.0143013