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Suppression of the Arboviruses Dengue and Chikungunya Using a Dual-Acting Group-I Intron Coupled with Conditional Expression of the Bax C-Terminal Domain

In portions of South Asia, vectors and patients co-infected with dengue (DENV) and chikungunya (CHIKV) are on the rise, with the potential for this occurrence in other regions of the world, for example the United States. Therefore, we engineered an antiviral approach that suppresses the replication...

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Detalles Bibliográficos
Autores principales: Carter, James R., Taylor, Samantha, Fraser, Tresa S., Kucharski, Cheryl A., Dawson, James L., Fraser, Malcolm J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651551/
https://www.ncbi.nlm.nih.gov/pubmed/26580561
http://dx.doi.org/10.1371/journal.pone.0139899