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Suppression of the Arboviruses Dengue and Chikungunya Using a Dual-Acting Group-I Intron Coupled with Conditional Expression of the Bax C-Terminal Domain
In portions of South Asia, vectors and patients co-infected with dengue (DENV) and chikungunya (CHIKV) are on the rise, with the potential for this occurrence in other regions of the world, for example the United States. Therefore, we engineered an antiviral approach that suppresses the replication...
Autores principales: | Carter, James R., Taylor, Samantha, Fraser, Tresa S., Kucharski, Cheryl A., Dawson, James L., Fraser, Malcolm J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651551/ https://www.ncbi.nlm.nih.gov/pubmed/26580561 http://dx.doi.org/10.1371/journal.pone.0139899 |
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