Functional Characterization of IPSC-Derived Brain Cells as a Model for X-Linked Adrenoleukodystrophy

X-ALD is an inherited neurodegenerative disorder where mutations in the ABCD1 gene result in clinically diverse phenotypes: the fatal disorder of cerebral childhood ALD (cALD) or a milder disorder of adrenomyeloneuropathy (AMN). The various models used to study the pathobiology of X-ALD disease lack...

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Detalles Bibliográficos
Autores principales: Baarine, Mauhamad, Khan, Mushfiquddin, Singh, Avtar, Singh, Inderjit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651558/
https://www.ncbi.nlm.nih.gov/pubmed/26581106
http://dx.doi.org/10.1371/journal.pone.0143238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651558/
https://www.ncbi.nlm.nih.gov/pubmed/26581106
http://dx.doi.org/10.1371/journal.pone.0143238

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