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Geometry Dynamics of α-Helices in Different Class I Major Histocompatibility Complexes

MHC α-helices form the antigen-binding cleft and are of particular interest for immunological reactions. To monitor these helices in molecular dynamics simulations, we applied a parsimonious fragment-fitting method to trace the axes of the α-helices. Each resulting axis was fitted by polynomials in...

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Detalles Bibliográficos
Autores principales: Ribarics, Reiner, Kenn, Michael, Karch, Rudolf, Ilieva, Nevena, Schreiner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651647/
https://www.ncbi.nlm.nih.gov/pubmed/26649324
http://dx.doi.org/10.1155/2015/173593