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MALT1 is required for EGFR induced NF-κB activation and contributes to EGFR-driven lung cancer progression

The transcription factor NF-κB has been implicated in playing a crucial role in the tumorigenesis of many types of human cancers. Although Epidermal Growth Factor Receptor (EGFR) can directly activate NF-κB, the mechanism by which EGFR induces NF-κB activation and the role of NF-κB in EGFR-associate...

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Detalles Bibliográficos
Autores principales: Pan, Deng, Jiang, Changying, Ma, Zhongliang, Blonska, Marzenna, You, M. James, Lin, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651666/
https://www.ncbi.nlm.nih.gov/pubmed/25982276
http://dx.doi.org/10.1038/onc.2015.146