DMA(V) in Drinking Water Activated NF-κB Signal Pathway and Increased TGF-β and IL-1β Expressions in Bladder Epithelial Cells of Rats

Dimethylarsinic acid (DMA(V)) is the main product of arsenic methylation metabolism in vivo and is rat bladder carcinogen and tumor promoting agent. In this study, we measured the expressions of mRNA and proteins of NF-κB pathway members, IKKα, IKKβ, p65, and p50 in rat bladder epithelium by qRT-PCR...

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Detalles Bibliográficos
Autores principales: Cao, Siqi, Liu, Shengnan, Wang, Fei, Liu, Jieyu, Li, Mengdan, Wang, Chen, Xi, Shuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651728/
https://www.ncbi.nlm.nih.gov/pubmed/26617437
http://dx.doi.org/10.1155/2015/790652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651728/
https://www.ncbi.nlm.nih.gov/pubmed/26617437
http://dx.doi.org/10.1155/2015/790652

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