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Stromal fibroblasts facilitate cancer cell invasion by a novel invadopodia-independent matrix degradation process

Metastatic invasion of tumors into peripheral tissues is known to rely upon protease-mediated degradation of the surrounding stroma. This remodeling process utilizes complex, actin-based, specializations of the plasma membrane termed invadopodia that act both to sequester and release matrix metallop...

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Detalles Bibliográficos
Autores principales: Cao, Hong, Eppinga, Robbin D., Razidlo, Gina L., Krueger, Eugene W., Chen, Jing, Qiang, Li, McNiven, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651864/
https://www.ncbi.nlm.nih.gov/pubmed/25982272
http://dx.doi.org/10.1038/onc.2015.163