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Stromal fibroblasts facilitate cancer cell invasion by a novel invadopodia-independent matrix degradation process
Metastatic invasion of tumors into peripheral tissues is known to rely upon protease-mediated degradation of the surrounding stroma. This remodeling process utilizes complex, actin-based, specializations of the plasma membrane termed invadopodia that act both to sequester and release matrix metallop...
Autores principales: | Cao, Hong, Eppinga, Robbin D., Razidlo, Gina L., Krueger, Eugene W., Chen, Jing, Qiang, Li, McNiven, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651864/ https://www.ncbi.nlm.nih.gov/pubmed/25982272 http://dx.doi.org/10.1038/onc.2015.163 |
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