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Adipose tissue macrophages induce PPARγ-high FOXP3(+) regulatory T cells

Numerous regulatory T cells (Tregs) are present in adipose tissues compared with other lymphoid or non-lymphoid tissues. Adipose Tregs regulate inflammatory state and insulin sensitivity. However, the mechanism that maintains Tregs in adipose tissue remains unclear. Here, we revealed the contributio...

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Detalles Bibliográficos
Autores principales: Onodera, Toshiharu, Fukuhara, Atsunori, Jang, Myoung Ho, Shin, Jihoon, Aoi, Keita, Kikuta, Junichi, Otsuki, Michio, Ishii, Masaru, Shimomura, Iichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652162/
https://www.ncbi.nlm.nih.gov/pubmed/26582486
http://dx.doi.org/10.1038/srep16801