Gγ recruitment systems specifically select PPI and affinity-enhanced candidate proteins that interact with membrane protein targets

Protein-protein interactions (PPIs) are crucial for the vast majority of biological processes. We previously constructed a Gγ recruitment system to screen PPI candidate proteins and desirable affinity-altered (affinity-enhanced and affinity-attenuated) protein variants. The methods utilized a target...

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Detalles Bibliográficos
Autores principales: Kaishima, Misato, Ishii, Jun, Fukuda, Nobuo, Kondo, Akihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652169/
https://www.ncbi.nlm.nih.gov/pubmed/26581329
http://dx.doi.org/10.1038/srep16723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652169/
https://www.ncbi.nlm.nih.gov/pubmed/26581329
http://dx.doi.org/10.1038/srep16723

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