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CpG island erosion, polycomb occupancy and sequence motif enrichment at bivalent promoters in mammalian embryonic stem cells

In embryonic stem (ES) cells, developmental regulators have a characteristic bivalent chromatin signature marked by simultaneous presence of both activation (H3K4me3) and repression (H3K27me3) signals and are thought to be in a ‘poised’ state for subsequent activation or silencing during differentia...

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Detalles Bibliográficos
Autores principales: Mantsoki, Anna, Devailly, Guillaume, Joshi, Anagha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652170/
https://www.ncbi.nlm.nih.gov/pubmed/26582124
http://dx.doi.org/10.1038/srep16791