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Slit2N Inhibits Transmission of HIV-1 from Dendritic Cells to T-cells by Modulating Novel Cytoskeletal Elements

Dendritic cells are among the first cells to encounter sexually acquired human immunodeficiency virus (HIV-1), in the mucosa, and they can transmit HIV-1 to CD4(+) T-cells via an infectious synapse. Recent studies reveal that actin-rich membrane extensions establish direct contact between cells at t...

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Detalles Bibliográficos
Autores principales: Shrivastava, Ashutosh, Prasad, Anil, Kuzontkoski, Paula M., Yu, Jinlong, Groopman, Jerome E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652184/
https://www.ncbi.nlm.nih.gov/pubmed/26582347
http://dx.doi.org/10.1038/srep16833