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Olfactomedin 4 deficiency promotes prostate neoplastic progression and is associated with upregulation of the hedgehog-signaling pathway

Loss of olfactomedin 4 (OLFM4) gene expression is associated with the progression of human prostate cancer, but its role and the molecular mechanisms involved in this process have not been completely understood. In this study, we found that Olfm4-knockout mice developed prostatic intraepithelial neo...

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Detalles Bibliográficos
Autores principales: Li, Hongzhen, Liu, Wenli, Chen, Weiping, Zhu, Jianqiong, Deng, Chu-Xia, Rodgers, Griffin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652203/
https://www.ncbi.nlm.nih.gov/pubmed/26581960
http://dx.doi.org/10.1038/srep16974