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Microgravity Reduces the Differentiation and Regenerative Potential of Embryonic Stem Cells

Mechanical unloading in microgravity is thought to induce tissue degeneration by various mechanisms, including inhibition of regenerative stem cell differentiation. To address this hypothesis, we investigated the effects of microgravity on early lineage commitment of mouse embryonic stem cells (mESC...

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Detalles Bibliográficos
Autores principales: Blaber, Elizabeth A., Finkelstein, Hayley, Dvorochkin, Natalya, Sato, Kevin Y., Yousuf, Rukhsana, Burns, Brendan P., Globus, Ruth K., Almeida, Eduardo A.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652210/
https://www.ncbi.nlm.nih.gov/pubmed/26414276
http://dx.doi.org/10.1089/scd.2015.0218