Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson’s disease genetically related mutants

Oligomers of alpha-synuclein are toxic to cells and have been proposed to play a key role in the etiopathogenesis of Parkinson’s disease. As certain missense mutations in the gene encoding for alpha-synuclein induce early-onset forms of the disease, it has been suggested that these variants might ha...

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Detalles Bibliográficos
Autores principales: Tosatto, Laura, Horrocks, Mathew H., Dear, Alexander J., Knowles, Tuomas P. J., Dalla Serra, Mauro, Cremades, Nunilo, Dobson, Christopher M., Klenerman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652217/
https://www.ncbi.nlm.nih.gov/pubmed/26582456
http://dx.doi.org/10.1038/srep16696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652217/
https://www.ncbi.nlm.nih.gov/pubmed/26582456
http://dx.doi.org/10.1038/srep16696

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