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Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson’s disease genetically related mutants

Oligomers of alpha-synuclein are toxic to cells and have been proposed to play a key role in the etiopathogenesis of Parkinson’s disease. As certain missense mutations in the gene encoding for alpha-synuclein induce early-onset forms of the disease, it has been suggested that these variants might ha...

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Detalles Bibliográficos
Autores principales:	Tosatto, Laura, Horrocks, Mathew H., Dear, Alexander J., Knowles, Tuomas P. J., Dalla Serra, Mauro, Cremades, Nunilo, Dobson, Christopher M., Klenerman, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652217/ https://www.ncbi.nlm.nih.gov/pubmed/26582456 http://dx.doi.org/10.1038/srep16696

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