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Linker histone H1.2 establishes chromatin compaction and gene silencing through recognition of H3K27me3
Linker histone H1 is a protein component of chromatin and has been linked to higher-order chromatin compaction and global gene silencing. However, a growing body of evidence suggests that H1 plays a gene-specific role, regulating a relatively small number of genes. Here we show that H1.2, one of the...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652225/ https://www.ncbi.nlm.nih.gov/pubmed/26581166 http://dx.doi.org/10.1038/srep16714 |