Light-assisted small molecule screening against protein kinases

High-throughput live-cell screens are intricate elements of systems biology studies and drug discovery pipelines. Here, we demonstrate an optogenetics-assisted method that obviates the addition of chemical activators and reporters, reduces the number of operational steps and increases information co...

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Detalles Bibliográficos
Autores principales: Inglés-Prieto, Álvaro, Reichhart, Eva, Muellner, Markus K., Nowak, Matthias, Nijman, Sebastian M., Grusch, Michael, Janovjak, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652335/
https://www.ncbi.nlm.nih.gov/pubmed/26457372
http://dx.doi.org/10.1038/nchembio.1933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652335/
https://www.ncbi.nlm.nih.gov/pubmed/26457372
http://dx.doi.org/10.1038/nchembio.1933

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