Cargando…
High-throughput sequencing insights into T-cell receptor repertoire diversity in aging
Decline in T-cell generation leading to T-cell receptor repertoire contraction is a cornerstone of immune system aging, and consequent disorders. High-throughput sequencing enables in-depth immune repertoire characterization, but blood samples are too small to capture its total diversity. New comput...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652363/ https://www.ncbi.nlm.nih.gov/pubmed/26582264 http://dx.doi.org/10.1186/s13073-015-0242-3 |