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antaRNA – Multi-objective inverse folding of pseudoknot RNA using ant-colony optimization

BACKGROUND: Many functional RNA molecules fold into pseudoknot structures, which are often essential for the formation of an RNA’s 3D structure. Currently the design of RNA molecules, which fold into a specific structure (known as RNA inverse folding) within biotechnological applications, is lacking...

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Detalles Bibliográficos
Autores principales: Kleinkauf, Robert, Houwaart, Torsten, Backofen, Rolf, Mann, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652366/
https://www.ncbi.nlm.nih.gov/pubmed/26581440
http://dx.doi.org/10.1186/s12859-015-0815-6