Comparison of targeted next-generation sequencing and Sanger sequencing for the detection of PIK3CA mutations in breast cancer

BACKGROUND: Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha, PIK3CA, is one of the most frequently mutated genes in breast cancer, and the mutation status of PIK3CA has clinical relevance related to response to therapy. The aim of our study was to investigate the mutation sta...

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Detalles Bibliográficos
Autores principales: Arsenic, Ruza, Treue, Denise, Lehmann, Annika, Hummel, Michael, Dietel, Manfred, Denkert, Carsten, Budczies, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652376/
https://www.ncbi.nlm.nih.gov/pubmed/26587011
http://dx.doi.org/10.1186/s12907-015-0020-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652376/
https://www.ncbi.nlm.nih.gov/pubmed/26587011
http://dx.doi.org/10.1186/s12907-015-0020-6

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