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Alzheimer’s disease cerebrospinal fluid biomarkers are not influenced by gravity drip or aspiration extraction methodology

INTRODUCTION: Cerebrospinal fluid (CSF) biomarkers, although of established utility in the diagnostic evaluation of Alzheimer’s disease (AD), are known to be sensitive to variation based on pre-analytical sample processing. We assessed whether gravity droplet collection versus syringe aspiration was...

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Detalles Bibliográficos
Autores principales: Rembach, Alan, Evered, Lisbeth A., Li, Qiao-Xin, Nash, Tabitha, Vidaurre, Lesley, Fowler, Christopher J., Pertile, Kelly K., Rumble, Rebecca L., Trounson, Brett O., Maher, Sarah, Mooney, Francis, Farrow, Maree, Taddei, Kevin, Rainey-Smith, Stephanie, Laws, Simon M., Macaulay, S. Lance, Wilson, William, Darby, David G., Martins, Ralph N., Ames, David, Collins, Steven, Silbert, Brendan, Masters, Colin L., Doecke, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652410/
https://www.ncbi.nlm.nih.gov/pubmed/26581886
http://dx.doi.org/10.1186/s13195-015-0157-7