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Peritumoural neutrophils negatively regulate adaptive immunity via the PD-L1/PD-1 signalling pathway in hepatocellular carcinoma
BACKGROUND: PD-L1 expression on neutrophils contributes to the impaired immune response in infectious disease, but the detailed role of PD-L1 expression on neutrophils in HCC remains unclear. METHODS: We investigated the phenotype and morphology of neutrophils infiltrated in tumour tissues from both...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652417/ https://www.ncbi.nlm.nih.gov/pubmed/26581194 http://dx.doi.org/10.1186/s13046-015-0256-0 |