Investigating bisulfite short-read mapping failure with hairpin bisulfite sequencing data

BACKGROUND: DNA methylation is an important epigenetic mark relevant to normal development and disease genesis. A common approach to characterizing genome-wide DNA methylation is using Next Generation Sequencing technology to sequence bisulfite treated DNA. The short sequence reads are mapped to the...

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Detalles Bibliográficos
Autores principales: Porter, Jacob, Sun, Ming-an, Xie, Hehuang, Zhang, Liqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652484/
https://www.ncbi.nlm.nih.gov/pubmed/26576456
http://dx.doi.org/10.1186/1471-2164-16-S11-S2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652484/
https://www.ncbi.nlm.nih.gov/pubmed/26576456
http://dx.doi.org/10.1186/1471-2164-16-S11-S2

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