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Molecular portraits: the evolution of the concept of transcriptome-based cancer signatures

Cancer results from dysregulation of multiple steps of gene expression programs. We review how transcriptome profiling has been widely explored for cancer classification and biomarker discovery but resulted in limited clinical impact. Therefore, we discuss alternative and complementary omics approac...

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Detalles Bibliográficos
Autores principales: Modelska, Angelika, Quattrone, Alessandro, Re, Angela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652618/
https://www.ncbi.nlm.nih.gov/pubmed/25832647
http://dx.doi.org/10.1093/bib/bbv013