Frequency-based haplotype reconstruction from deep sequencing data of bacterial populations

Clonal populations accumulate mutations over time, resulting in different haplotypes. Deep sequencing of such a population in principle provides information to reconstruct these haplotypes and the frequency at which the haplotypes occur. However, this reconstruction is technically not trivial, espec...

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Detalles Bibliográficos
Autores principales: Pulido-Tamayo, Sergio, Sánchez-Rodríguez, Aminael, Swings, Toon, Van den Bergh, Bram, Dubey, Akanksha, Steenackers, Hans, Michiels, Jan, Fostier, Jan, Marchal, Kathleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652744/
https://www.ncbi.nlm.nih.gov/pubmed/25990729
http://dx.doi.org/10.1093/nar/gkv478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652744/
https://www.ncbi.nlm.nih.gov/pubmed/25990729
http://dx.doi.org/10.1093/nar/gkv478

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