MicroRNA-29b/Tet1 regulatory axis epigenetically modulates mesendoderm differentiation in mouse embryonic stem cells

Ten eleven translocation (Tet) family-mediated DNA oxidation on 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) represents a novel epigenetic modification that regulates dynamic gene expression during embryonic stem cells (ESCs) differentiation. Through the role of Tet on 5hmC regulation in...

Descripción completa

Detalles Bibliográficos
Autores principales: Tu, Jiajie, Ng, Shuk Han, Shui Luk, Alfred Chun, Liao, Jinyue, Jiang, Xiaohua, Feng, Bo, Lun Mak, Kingston King, Rennert, Owen M., Chan, Wai-Yee, Lee, Tin-Lap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652748/
https://www.ncbi.nlm.nih.gov/pubmed/26130713
http://dx.doi.org/10.1093/nar/gkv653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652748/
https://www.ncbi.nlm.nih.gov/pubmed/26130713
http://dx.doi.org/10.1093/nar/gkv653

Ejemplares similares