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MicroRNA-29b/Tet1 regulatory axis epigenetically modulates mesendoderm differentiation in mouse embryonic stem cells

Ten eleven translocation (Tet) family-mediated DNA oxidation on 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) represents a novel epigenetic modification that regulates dynamic gene expression during embryonic stem cells (ESCs) differentiation. Through the role of Tet on 5hmC regulation in...

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Detalles Bibliográficos
Autores principales:	Tu, Jiajie, Ng, Shuk Han, Shui Luk, Alfred Chun, Liao, Jinyue, Jiang, Xiaohua, Feng, Bo, Lun Mak, Kingston King, Rennert, Owen M., Chan, Wai-Yee, Lee, Tin-Lap
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652748/ https://www.ncbi.nlm.nih.gov/pubmed/26130713 http://dx.doi.org/10.1093/nar/gkv653

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