A design principle for a single-stranded RNA genome that replicates with less double-strand formation

Single-stranded RNA (ssRNA) is the simplest form of genetic molecule and constitutes the genome in some viruses and presumably in primitive life-forms. However, an innate and unsolved problem regarding the ssRNA genome is formation of inactive double-stranded RNA (dsRNA) during replication. Here, we...

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Detalles Bibliográficos
Autores principales: Usui, Kimihito, Ichihashi, Norikazu, Yomo, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652763/
https://www.ncbi.nlm.nih.gov/pubmed/26202975
http://dx.doi.org/10.1093/nar/gkv742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652763/
https://www.ncbi.nlm.nih.gov/pubmed/26202975
http://dx.doi.org/10.1093/nar/gkv742

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