Free energy landscape and transition pathways from Watson–Crick to Hoogsteen base pairing in free duplex DNA

Houghton (HG) base pairing plays a central role in the DNA binding of proteins and small ligands. Probing detailed transition mechanism from Watson–Crick (WC) to HG base pair (bp) formation in duplex DNAs is of fundamental importance in terms of revealing intrinsic functions of double helical DNAs b...

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Detalles Bibliográficos
Autores principales: Yang, Changwon, Kim, Eunae, Pak, Youngshang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652778/
https://www.ncbi.nlm.nih.gov/pubmed/26250116
http://dx.doi.org/10.1093/nar/gkv796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652778/
https://www.ncbi.nlm.nih.gov/pubmed/26250116
http://dx.doi.org/10.1093/nar/gkv796

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